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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RIPK4
All Species:
22.73
Human Site:
Y37
Identified Species:
50
UniProt:
P57078
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57078
NP_065690
832
91611
Y37
S
G
G
F
G
Q
V
Y
K
V
R
H
V
H
W
Chimpanzee
Pan troglodytes
XP_001134659
786
86619
Y37
S
G
G
F
G
Q
V
Y
K
V
R
H
V
H
W
Rhesus Macaque
Macaca mulatta
XP_001107026
786
86655
Y37
S
G
G
F
G
Q
V
Y
K
V
R
H
V
H
W
Dog
Lupus familis
XP_544897
826
90932
K79
A
A
S
G
R
C
Y
K
V
P
P
D
V
H
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERK0
786
86594
Y37
S
G
G
F
G
Q
V
Y
K
V
R
H
V
H
W
Rat
Rattus norvegicus
P0C8E4
606
67182
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511321
791
87316
Y38
S
G
G
F
G
Q
V
Y
K
V
R
H
V
H
W
Chicken
Gallus gallus
XP_416738
789
87316
Y37
S
G
G
F
G
Q
V
Y
K
V
R
H
L
H
W
Frog
Xenopus laevis
NP_001080415
720
79835
E27
S
R
E
F
C
G
W
E
K
V
G
S
G
G
F
Zebra Danio
Brachydanio rerio
Q502K3
1071
114412
H46
Q
E
R
R
T
P
L
H
A
A
A
W
L
G
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001180763
1378
147477
P41
F
A
A
Q
K
G
H
P
D
V
T
K
Y
L
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.5
92.6
83.2
N.A.
84.9
23
N.A.
77.5
72.1
61.6
22
N.A.
N.A.
N.A.
N.A.
21.4
Protein Similarity:
100
93.9
93.5
88.3
N.A.
89.3
38.9
N.A.
85.6
83.7
72.9
35.8
N.A.
N.A.
N.A.
N.A.
34.9
P-Site Identity:
100
100
100
20
N.A.
100
0
N.A.
100
93.3
26.6
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
26.6
N.A.
100
0
N.A.
100
100
33.3
20
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
19
10
0
0
0
0
0
10
10
10
0
0
0
0
% A
% Cys:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
10
% D
% Glu:
0
10
10
0
0
0
0
10
0
0
0
0
0
0
0
% E
% Phe:
10
0
0
64
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
55
55
10
55
19
0
0
0
0
10
0
10
19
0
% G
% His:
0
0
0
0
0
0
10
10
0
0
0
55
0
64
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
10
0
0
10
64
0
0
10
0
0
0
% K
% Leu:
0
0
0
0
0
0
10
0
0
0
0
0
19
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
10
0
10
0
10
10
0
0
0
0
% P
% Gln:
10
0
0
10
0
55
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
10
10
10
0
0
0
0
0
55
0
0
0
0
% R
% Ser:
64
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% S
% Thr:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
55
0
10
73
0
0
55
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
64
% W
% Tyr:
0
0
0
0
0
0
10
55
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _